Denver Advanced Neurological Treatment Center


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1721 East 19th Avenue, Suite 510, Denver, CO 80218

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Klippel-Trenaunay Syndrome (KTS)

What is Klippel-Trenaunay Syndrome (KTS)?

Klippel-Trenaunay syndrome (KTS) is a congenital circulatory disorder characterized by hemangiomas (abnormal benign growths on the skin consisting of masses of blood vessels), arteriovenous abscesses, and varicose veins, usually on the limbs. The affected limbs may be enlarged and warmer than normal. Fused toes or fingers, or extra toes or fingers, may be present. Bleeding may occur, often as a result of a rectal or vaginal tumor. The cause of the disorder is unknown. A similar port-wine stain disorder in which individuals have vascular anomalies and limb enlargement is Sturge-Weber syndrome. These patients may experience seizures and mental deficiency.

Is there any treatment?

There is no cure for KTS. Treatment is symptomatic. Laser surgery can diminish or erase some skin lesions. Surgery may correct discrepancies in limb size, but orthopedic devices may be more appropriate.

What is the prognosis?

KTS is a progressive disorder, and complications may be life-threatening.

What research is being done?

The NINDS supports research on congenital disorders such as KTS with the goal of finding new means to treat and prevent them.


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