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Absence of the Septum Pellucidum

What is Absence of the Septum Pellucidum?

The septum pellucidum (SP) is a thin membrane located at the midline of the brain. Children who are born without this membraine and also have other abnormalities--pituitary deficiencies and abnormal development of the optic disk--have a disorder known as septo-optic dysplasia.

Is there any treatment?

Absence of the SP alone is not a disorder but is instead a characteristic noted in children with septo-optic dysplasia.

What is the prognosis?

The absence of the septum pellucidum alone is not a disorder. However, when it is part of septo-optic dysplasia the prognosis varies according to the presence and severity of associated symptoms.

What research is being done?

The NINDS conducts and supports a wide range of studies that explore the complex mechanisms of normal brain development. The knowledge gained from these fundamental studies provides the foundation for understanding how this process can go awry and, thus, offers hope for new means to treat and prevent developmental brain disorders.

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